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What Does the Membrane Expansion Theory of the Action of Local

Question 2

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What does the membrane expansion theory of the action of local anesthetics suggest?


A) Anesthetics that are highly hydrophilic cause the matrix of the nerve membrane to expand, narrowing the sodium channels, thus preventing depolarization.
B) Anesthetics that are highly lipid soluble cause the lipoprotein matrix of the nerve membrane to expand, narrowing the sodium channels, thus preventing depolarization.
C) Anesthetics cause the sodium channels to expand, thus allowing the increase in protein binding within the channels.
D) All of the above

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