In Graves Disease (Hyperthyroidism), Autoantibodies Bind to and Activate Receptors

Multiple Choice

In Graves disease (hyperthyroidism) , autoantibodies bind to and activate receptors for thyroid-stimulating hormone (TSH) so that excessive T₄ (thyroxine) is secreted, causing clinical manifestations of an increased metabolism.This mechanism is an example of which type II hypersensitivity reaction?

A) Modulation
B) ADCC
C) Neutrophil-mediated damage
D) Complement-mediated lysis