What Explains Anchorage Dependence of Animal Cells in Vitro or in Vivo

Multiple Choice

What explains anchorage dependence of animal cells in vitro or in vivo?

A) attachment of spindle fibres to centrioles
B) response of the plasma membrane to cell cycle controls
C) the makeup of the extracellular matrix of the substrate
D) the binding of cell-surface phospholipids to those of adjoining cells
E) the binding of cell-surface phospholipids to the substrate