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Two Competing Hypotheses to Account for the Increase in the Number

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Two competing hypotheses to account for the increase in the number of Hox genes from the last common ancestor of bilaterians to the last common ancestor of insects and vertebrates are (1) a single duplication of the entire four-gene cluster, followed by the loss of one gene, and (2) three independent duplications of individual Hox genes. To prefer the first hypothesis on the basis of parsimony requires the assumption that


A) the duplication of a cluster of four Hox genes is equally as likely as the duplication of a single Hox gene.
B) there is an actual process by which individual genes can be duplicated.
C) genes can exist is spatial groupings called clusters.
D) clusters of genes can undergo disruption, with individual genes moving to different chromosomes during evolution.

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