A Boy Showed Extensive Skin Blistering Shortly After Birth, with Large

Multiple Choice

A boy showed extensive skin blistering shortly after birth, with large areas of epidermis detaching from the dermis.Treatment with high doses of morphine was started to alleviate the seemingly excruciating pain suffered by the infant.Histological analysis shows that the basement membrane appeared intact in fresh blisters, but the stratum germinativum was destroyed.This type of disease is most likely caused by defects in which protein?

A) Desmin.
B) Tubulin.
C) Elastin.
D) Keratin.
E) Dystrophin.