Amethopterin (Methotrexate) and Fluorouracil Are Two Drugs That Are Sometimes

Multiple Choice

Amethopterin (methotrexate) and fluorouracil are two drugs that are sometimes used in combination for cancer chemotherapy.Which of the following processes is inhibited by both of these drugs?

A) Reduction of ribonucleotides to deoxyribonucleotides.
B) Synthesis of purine nucleotides.
C) De novo synthesis of pyrimidine nucleotides.
D) Synthesis of thymine.
E) Polymerization of tubulin.