What Is the Mechanism by Which Toxic Shock Syndrome Toxin-1

Multiple Choice

What is the mechanism by which toxic shock syndrome toxin-1 (TSST-1) causes toxic shock syndrome (TSS) ?

A) The bacteria release the toxin into the blood and it goes to the hypothalamus to produce an extremely high fever.
B) The bacteria release the toxin into the gastrointestinal system where phagocytes engulf the bacteria, leaving a pseudomembrane that irritates the colon.
C) The toxin is a superantigen that stimulates T-cell proliferation with production of large amounts of cytokines.
D) All of the above.