A Researcher Interested in Patterning of the Early Neural Tube

Multiple Choice

A researcher interested in patterning of the early neural tube identifies a new secreted factor expressed in the isthmus signaling center.Assuming that the newly identified factor plays a role in patterning,which axis of the developing neural tube would you expect to be perturbed if this factor is inactivated?

A) Cranial-caudal
B) Dorsal-ventral
C) Medial-lateral
D) Right-left