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Starting Translation at the Authentic (Correct) Start Codon Is Essential

Question 41

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Starting translation at the authentic (correct) start codon is essential for translation of the correct polypeptide. Errant translation starting at the wrong codon, or even at the wrong nucleotide of the start codon, may produce an abnormal polypeptide and result in a nonfunctional protein. Compare and contrast the mechanisms used by bacteria and eukaryotes to identify the authentic start codon during translation initiation.

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In bacteria (specifically E. coli), six ...

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