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When a Transgene Is Used in Mice to Knock Out

Question 42

Multiple Choice

When a transgene is used in mice to knock out a specific function, two problems that might occur are the unintended introduction of multiple copies or abnormal gene expression. The second of these problems is related to __________.


A) position effect
B) homologous recombination
C) vector insufficiency
D) mitotic recombination
E) unequal crossing over

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