You Are a Genetic Counselor Working with a Phenotypically Normal

Multiple Choice

You are a genetic counselor working with a phenotypically normal young couple who have been referred because the wife has a family history of a mitochondrial disorder that results in considerable dysfunction. What is the most important consideration you can suggest?

A) to refrain from having children that are hers biologically
B) that she be tested to find out what percentage of her mitochondria bear the mutation
C) that both husband and wife have mtDNA testing for the sequence in question
D) that her affected mother's DNA be tested
E) that they consider having only sons