Which of the Following Is a Methodological Issue That Arises

Multiple Choice

Which of the following is a methodological issue that arises in studies investigating cerebral laterality in split-brain patients?

A) Due to their epilepsy, these people may not have had normal brain organization before surgery.
B) The size of the corpus callosum and the effects of severing it are too variable.
C) Sectioning the corpus callosum causes severe behavioral side effects that make research participation difficult.
D) Each person's physiological response to the surgery is different and creates new patterns of brain organization during recovery.