Why Does Folate or Vitamin B₁₂ Deficiency Lead to Macrocytic

Multiple Choice

Why does folate or vitamin B₁₂ deficiency lead to macrocytic anemia?

A) because reduced hemoglobin synthesis will produce cells of inadequate size
B) because poor DNA synthesis will impair blood cells' ability to divide
C) because red blood cell precursors (stem cells) will proliferate in the bone marrow
D) because white blood cells (leukocytes) will proliferate in the bone marrow