Why Does B-Cell Proliferation and Differentiation Often Require Assistance from Helper

Multiple Choice

Why does B-cell proliferation and differentiation often require assistance from helper T cells?

A) Capping does not occur unless epitopes are found in multiple copies.
B) B cells require antigen presentation by helper T cells.
C) Microbes often destroy B-cell receptors and then B cells require help from T cells.
D) Helper T cells are required to move epitopes closer together for capping by B cells.