Why Might an Opioid with Substantial Lipid Solubility Be a Preferred

Multiple Choice

Why might an opioid with substantial lipid solubility be a preferred recreational substance to an opioid with poor lipid solubility?

A) The poor lipid solubility drug doesn't bind well to opioid receptors.
B) The poor lipid solubility drug will be metabolized more quickly.
C) The poor lipid solubility drug passes more slowly through the blood-brain barrier.
D) The poor lipid solubility drug is rapidly eliminated from the body.