A Healthcare Professional Is Teaching a Patient About Raynaud Phenomenon

Multiple Choice

A healthcare professional is teaching a patient about Raynaud phenomenon and instructs the patient to avoid cold. What is the best explanation of how cold impacts the manifestations of this disease?

A) Immune complexes that are deposited in capillary beds, blocking circulation
B) Mast cells that are bound to specific endothelial receptors, causing them to degranulate and creating a localized inflammatory reaction that occludes capillary circulation
C) Cytotoxic T cells that attack and destroy the capillaries so that they are unable to perfuse local tissues
D) Antibodies that detect the capillaries as foreign protein and destroy them using lysosomal enzymes and toxic oxygen species