How Does Hemolytic Disease of the Fetus and Newborn (HDFN)

Multiple Choice

How does hemolytic disease of the fetus and newborn (HDFN) cause acquired congenital hemolytic anemia?

A) HDFN develops when hypoxia or dehydration causes the erythrocytes to change shapes, which are then recognized as foreign and removed from circulation.
B) HDFN is an alloimmune disease in which the mother's immune system produces antibodies against fetal erythrocytes, which are recognized as foreign and removed from circulation.
C) HDFN develops when the polycythemia present in fetal life continues after birth, causing the excessive number of erythrocytes to be removed from circulation.
D) HDFN is an autoimmune disease in which the fetus's immune system produces antibodies against fetal erythrocytes, which are recognized as foreign and removed from circulation.