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What Abnormalities Lead to the Mucus Plugging Seen in Children

Question 13

Multiple Choice

What abnormalities lead to the mucus plugging seen in children with cystic fibrosis (CF) ?


A) Excess mucus plugs the gut and keeps it from absorbing water effectively.
B) A weak inflammatory response allows bacterial to colonize the mucus.
C) Defective chloride secretion and excess sodium absorption thicken the mucus.
D) Pulmonary vascular remodeling occurs that leads to chronic hypoxia.

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