How Might a Change in DNA Nucleotide Sequence of a Gene

Multiple Choice

How might a change in DNA nucleotide sequence of a gene cause a genetic disorder?

A) A change in one base pair in a gene can change a crucial amino acid in a protein.
B) A mutation can change the three-dimensional shape of a protein and cause defective protein folding.
C) A mutational change can cause a protein's subunits not to couple with each other properly.
D) The change can lead to production of a shortened, non-functional protein.
E) All of these are possible ways that changes in DNA could lead to genetic disorders.