SV40 Was the First Virus Used to Express a Foreign

Multiple Choice

SV40 was the first virus used to express a foreign protein in a cultured cell.But SV40 has which of the following limitations?

A) The small genome can only accommodate a small gene.
B) It can only infect monkey cells.
C) It does not integrate its genome into the host cell genome.
D) It replicates very slowly.
E) It does not have a strong promoter/enhancer for gene expression.