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The Reverse Transcription of HIV RNA Utilizes Host Cell TRNA

Question 22

Multiple Choice

The reverse transcription of HIV RNA utilizes host cell tRNA as a primer. Specifically, a tRNA for lysine is utilized. Would a drug that blocked the host cell synthesis of the tRNA for lysine be a good drug to prevent the HIV life cycle?


A) Yes, it should stop the reverse transcription of the HIV genome with few side effects.
B) No, the virus would just use a different tRNA for priming.
C) No, this would likely kill the cells that were drug treated, because they couldn't appropriately incorporate lysine into their proteins.
D) No, the priming function of the tRNA is not essential for the HIV life cycle.

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