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In Muscle Cells,the Following Reaction Proceeds as Written,i

Question 19

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In muscle cells,the following reaction proceeds as written,i.e.,from left to right,despite having DG°' » +30 kJ/mol.How can this occur? malate + NAD+ oxaloacetate + NADH + H+


A) It is obviously thermodynamically favored under standard conditions.
B) In the cell, it is kinetically favored, even though it's thermodynamically unfavored.
C) The concentration of malate must be higher than oxaloacetate for this reaction to occur in the cell.
D) [H+] must be higher in muscle than under standard conditions, thus altering DG°' to DG°.

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