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Which of the Following Statements Best Describes the Difference Between

Question 11

Multiple Choice

Which of the following statements best describes the difference between low-affinity integrins and high-affinity integrins?


A) Many integrins can exist in two conformations: a low-affinity (bent) conformation and a high-affinity (straight) conformation.
B) Dissociation of the αβ heterodimer converts many integrins from the low-affinity to the high-affinity state.
C) Association of the αβ heterodimer converts many integrins from the low-affinity to the high-affinity state.
D) Proteolytic cleavage of the C-terminal tails of the two subunits converts many integrins from the low-affinity to the high-affinity state.

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