Which of the Following Is Least Likely to Occur from the Inactivation

Multiple Choice

Which of the following is least likely to occur from the inactivation of p53?

A) The appearance of homogenously staining regions on chromosomes
B) Increased propensity to arrest in G₁
C) alterations in the G₁ to S checkpoint
D) An increase in gene amplification in affected cells
E) Generation of fragments of chromosomal DNA lacking telomeres and centromeres