Which of the Following Is Not a Piece of Evidence

Multiple Choice

Which of the following is not a piece of evidence that supports the radial loop-scaffold model of DNA packaging?

A) Histone-depleted metaphase chromosomes still maintain their X-like shapes.
B) Electron micrographs of whole-mounted mitotic chromosomes show loops of chromatin at the periphery of the chromosomes.
C) Topoisomerase II assists in 100Å packaging.
D) Special, irregularly spaced repetitive base sequences associate with nonhistone proteins to define the chromatin loops.