Familial Hypercholesterolemia Is a Genetic Disease That Affects Approximately One

Multiple Choice

Familial hypercholesterolemia is a genetic disease that affects approximately one in 500 people worldwide.There is more than one genetic cause of the disease.Class I is often described as an autosomal dominant disease.Affected individuals have cholesterol levels >250 as children and often >300 as adults.However,homozygotes have cholesterol levels of >600 as children and can die of heart attacks in their 20s.These individuals entirely lack a functional LDL receptor.Which of the following would be the best description of the inheritance of this form of hypercholesterolemia?

A) Dominant epistatic
B) Codominant
C) Incompletely dominant
D) Complementary
E) Recessive epistatic