Excess Alcohol Consumption Can Lead to Wernicke-Korsaff Syndrome Due to the Lack

Multiple Choice

Excess alcohol consumption can lead to Wernicke-Korsaff syndrome due to the lack of the vitamin thiamine. Which of the following metabolic conversions CANNOT occur in the absence of thiamine?

A) pyruvate + CO₂ $\rightarrow$ oxaloacetate
B) pyruvate $\rightarrow$ acetyl-CoA + CO₂
C) $\alpha$ -ketoglutarate $\rightarrow$ succinyl-CoA + CO₂
D) phosphoenolpyruvate + CO₂ $\rightarrow$ oxaloacetate
E) B and C are correct.