Which of the Following Would Provide the Longest Lasting Treatment

Multiple Choice

Which of the following would provide the longest lasting treatment for Leber's congenital amaurosis II?

A) Replacing an enzyme that restores the function of T and B cells
B) Substrate reduction therapy and pharmacological chaperone therapy
C) Injecting adeno-associated virus carrying ornithine transcarbamylase (OTC) into T and B cells
D) Injecting adeno-associated virus carrying a wild type version of the RPE65 gene into affected cells of the retina