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Polymyxins Are Antibiotics That Bind to Lipopolysaccharide (LPS)in the Outer

Question 7

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Polymyxins are antibiotics that bind to lipopolysaccharide (LPS) in the outer membrane of Gram-negative bacteria,disrupting both the outer and inner membranes.The hydrophobic tail is important in causing membrane damage,suggesting a detergent-like mode of action.Why doesn't polymyxin also damage human membranes?


A) Because human cells do not have inner and outer membranes
B) Because human membranes do not contain LPS
C) Because human cells do not have cell walls
D) Because human membranes have enzymes that degrade LPS
E) Because bacterial membranes do not contain phospholipids like human membranes

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