What Is the Correct Order of the Following Steps in the Progression

Multiple Choice

What is the correct order of the following steps in the progression of lung cancer in a smoker? 1.Cilia are lost.2.There is a thickening and callusing of the cells lining the bronchi.3.Metastasis occurs.4.A tumor forms.5.Cells with atypical nuclei appear.

A) 1,2,3,4,5
B) 2,1,5,4,3
C) 5,1,2,3,4
D) 1,2,4,3,5
E) 2,1,4,5,3