Which of the Following Best Describes a Typical Mechanism for an Enzyme-Catalyzed

Multiple Choice

Which of the following best describes a typical mechanism for an enzyme-catalyzed reaction?

A) Slow formation of an enzyme-substrate complex, then fast formation of products and regeneration of enzyme
B) Fast formation of an enzyme-substrate complex, then slow formation of products and regeneration of enzyme
C) Slow binding of a cofactor to the substrate, then fast reaction with the enzyme to form an enzyme-substrate complex
D) Fast binding of a cofactor to the substrate, then slow reaction with the enzyme to form an enzyme-substrate complex
E) Slow formation of regenerated enzyme, then fast formation of products