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Explain Which Measures Led to the Development of Resistance to Amantadine

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Explain which measures led to the development of resistance to amantadine and rimantadine in the H5N1 influenza virus and why this resistance is a problem.Are there any alternative drugs to combat H5N1 and,if so,could sufficient protection be provided if there was an influenza pandemic?

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The antiviral drugs amantadine and riman...

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