Which of the Following Is/are True of Antibiotic Usage and the Development

Multiple Choice

Which of the following is/are true of antibiotic usage and the development of antibiotic resistance?

A) Antibiotics cause mutations (antibiotics are mutagens) , thus resulting in increasingly resistant bacterial populations.
B) Antibiotics increase the rate of bacterial transformation, conjugation, and transduction, and thus increase the spread of antibiotic resistance.
C) Antibiotics cause R-plasmids to form and cause their transfer, spreading antibiotic resistance.
D) Antibiotics select for resistant mutants and bacteria possessing R-plasmids, increasing their frequency in the population.
E) All of these choices are correct.