Apart from Bringing the Reactants Close Together,how Does the Binding

Multiple Choice

Apart from bringing the reactants close together,how does the binding of substrates in the active site of the enzyme serve to catalyze a reaction?

A) Binding lowers the activation energy of the reaction.
B) Enzymes provide energy upon substrate binding to drive the reaction.
C) Binding of the substrate maintains the optimal temperature for the reaction.
D) Binding maintains the optimal pH for enzyme activity.
E) Binding lowers the energy of the products increasing the reaction rate.