An Oncogene Is More Likely to Lead to Cancer Than

Multiple Choice

An oncogene is more likely to lead to cancer than a mutant tumor suppressor because

A) a gain of function mutation in an oncogene need only occur in one allele before it disrupts control of the cell cycle.
B) a loss of function mutation in an oncogene is sufficient to cause unregulated cell division.
C) the mutant oncogene may inactivate telomerase.
D) a gain of function mutation in a tumor suppressor gene can promote the cell cycle.
E) a gain of function mutation in an oncogene is more likely to cause the other allele to mutate.