What Is the Correct Order of the Steps in the Progression

Multiple Choice

What is the correct order of the steps in the progression of lung cancer in a smoker?
1) Cilia are lost
2) There is a thickening and callusing of the cells lining the bronchi
3) Metastasis occurs
4) A tumor forms
5) Cells with atypical nuclei appear

A) 1, 2, 3, 4, 5
B) 2, 1, 5, 4, 3
C) 5, 1, 2, 3, 4
D) 1, 2, 4, 3, 5
E) 2, 1, 4, 5, 3