Based on the Following, What Can Be Said About the Synthesis

Multiple Choice

Based on the following, what can be said about the synthesis of polynucleotides?

A) polynucleotides are unstable and are rapidly degraded
B) polynucleotide formation is made much more exergonic by the hydrolysis of pyrophosphate
C) the hydrolysis of nucleoside triphosphates is the only driving force to make an overall irreversible reaction
D) polynucleotides are highly resistant to hydrolysis, even in the presence of an acid catalyst
E) none of the above