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The Hydrolysis of Creatine Phosphate Is Coupled with the Synthesis

Question 49

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The hydrolysis of creatine phosphate is coupled with the synthesis of ATP.The equations for the reactions are given below.Would this coupling be favored?
Creatine phosphate + H2O → Creatine + HOPO3-2 ΔG = -10.3 kcal/mol
ADP + HOPO3-2 + H+ → ATP + H2O ΔG = +7.3 kcal/mol

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Add the two equations to get:
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