Which of the Following Is (Are)the Result of Insulin Binding

Multiple Choice

Which of the following is (are) the result of insulin binding to its receptor?
(I) MAPK activation,which regulates gene expression via Fos,Jun and Myc.
(II) PI3K activation leading to an increase in glucose transport.
(III) High affinity binding of SH2 domains to phosphorylated tyrosines.
(IV) Autophosphorylation resulting in activation of tyrosine kinase.

A) II,III,IV
B) I,II,III,IV
C) II,III
D) I,II
E) III only