Bacteria Have Obtained The $\beta$ -Lactamase Gene Which Encodes a Protein That Renders All

Multiple Choice

Bacteria have obtained the $\beta$ -lactamase gene which encodes a protein that renders all $\beta$ -lactem antibodies such as ampicillin and penicillin inactive.Which of the following would result in an increased number of bacteria with this ability?
(I) a transposon with the $\beta$ -lactamase gene
(II) a recombination event within the original strain that results in a point mutation inactivating $\beta$ -lactamase
(III) an insertion in the original strain rendering transposase inactive
(IV) a deletion in the insertion sequence of the transposon

A) I,II,III,IV
B) I only
C) II only
D) II,III
E) III,IV