Which of the Following Is True for the Procedures of Both

Multiple Choice

Which of the following is true for the procedures of both chromosome walking and chromosome jumping?
1) It is initiated by using a molecular probe such as an RFLP as a starting point
2) DNA fragments are prepared by partial digestion with a restriction enzyme
3) Genomic fragments are circularized using DNA Ligase

A) 1
B) 2
C) 3
D) 1 and 3
E) All of these