RNA Polymerase Can Transcribe in Different Directions on a Chromosome

Multiple Choice

RNA polymerase can transcribe in different directions on a chromosome.This is enabled because:

A) genes and their associated promoters can be oriented in either direction along a chromosome.
B) RNA polymerase can transcribe from either strand of DNA,synthesizing RNA in the 5′ to 3′ direction.
C) the chemistry of RNA synthesis is identical regardless of which strand is transcribed.
D) the 3′ end of a gene is always the template strand.
E) All of the answer options are correct.