In the 1940s,George Beadle and Edward Tatum Developed the One-Gene-One-Polypeptide

Multiple Choice

In the 1940s,George Beadle and Edward Tatum developed the one-gene-one-polypeptide hypothesis by mutating the genes of Neurospora crassa (bread mold) .They identified mutants that were unable to synthesize amino acids,such as arginine.When multiple mutant strains were identified for a single trait (adenine synthesis deficient) ,they showed that:

A) all the mutants encoded the same single enzyme.
B) genes were transcribed before being translated.
C) each step in the biochemical pathway was mediated by an enzyme encoded by a single gene.
D) the biosynthesis of arginine could occur,even with mutated enzymes.
E) separate genes/enzymes performed identical steps in the pathway.