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Which of the Following Correctly Explains Why Two Equivalents of Amine

Question 12

Multiple Choice

Which of the following correctly explains why two equivalents of amine are required for the aminolysis reaction shown below,while alcoholysis requires only one equivalent of alcohol? Which of the following correctly explains why two equivalents of amine are required for the aminolysis reaction shown below,while alcoholysis requires only one equivalent of alcohol?   A) Amines are less nucleophilic than alcohols. B) One equivalent of amine acts as a base and is irreversibly protonated. C) Alcohols are stronger bases than amines. D) Inductive effects from the Cl make the carbonyl C less electrophilic in aminolysis than in alcoholysis. E) Two molecules of amine are involved in the rate-determining step.


A) Amines are less nucleophilic than alcohols.
B) One equivalent of amine acts as a base and is irreversibly protonated.
C) Alcohols are stronger bases than amines.
D) Inductive effects from the Cl make the carbonyl C less electrophilic in aminolysis than in alcoholysis.
E) Two molecules of amine are involved in the rate-determining step.

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