Which of the Following Explains the Kinetic Stability of ATP

Multiple Choice

Which of the following explains the kinetic stability of ATP?

A) The hydrolysis of ATP occurs rapidly in the absence of a catalyst because the phosphate bonds are thermodynamically labile.
B) ATP is positively charged at physiological pH.
C) Water,the major component of cytoplasm,is a strong and very reactive nucleophile.
D) ATP is negatively charged at physiological pH and thus repels the approach of nucleophiles.
E) none of the above