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The Peptide Leu─Cys─Arg─Ser─Gln─Met Is Subjected to Edman Degradation

Question 12

Multiple Choice

The peptide Leu─Cys─Arg─Ser─Gln─Met is subjected to Edman degradation.In the first cycle the peptide first reacts with phenylisothiocyanate under basic conditions.The product of this reaction is incubated with anhydrous trifluoroacetic acid and subsequently with an aqueous acid.What are the products generated in the first cycle.


A) PTH─Leu,PTH─Cys,PTH─Arg,PTH─Ser,PTH─Gln,and PTH─Met
B) PTH─Leu─Cys─Arg─Ser─Gln─Met
C) PTH─Met and Leu─Cys─Arg─Ser─Gln─Met
D) PTH─Leu─Cys and PTH─Arg─Ser─Gln─Met
E) PTH─Leu and Cys─Arg─Ser─Gln─Met

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