Conventional One Dimensional NMR Spectroscopy Is Not Generally an Effective

Multiple Choice

Conventional one dimensional NMR spectroscopy is not generally an effective tool for determination of protein structure because…
(I) Proteins (including small proteins) have a high number of hydrogen atoms.
(II) NMR requires a high quality protein crystal.
(III) The NMR spectra exhibit high peak overlap.

A) I and II
B) II and III
C) I and III
D) I,II,and III
E) III only