Which Best Describes the Synthesis of Purine Nucleotides

Multiple Choice

Which best describes the synthesis of purine nucleotides?

A) The basic ring structure,orotate,is synthesized and then linked to PRPP.This is then modified to produce either GMP or AMP.
B) The basic ring structure,inosine,is synthesized and then linked to PRPP.This is then modified to produce either GMP or AMP.
C) The basic ring structure,orotate,is synthesized stepwise on PRPP.This is then modified to produce either GMP or AMP.
D) The basic ring structure,inosine,is synthesized stepwise on PRPP.This is then modified to produce either GMP or AMP.
E) The basic ring structure,orotate,is synthesized and then linked to PRPP.This is then modified to produce either UMP or CMP.