Which Is TRUE Regarding Structure and Function of RNAPII

Multiple Choice

Which is TRUE regarding structure and function of RNAPII?
(I) Distortion of the DNA by ~90° isolates the template base such that it can be properly paired.
(II) The "clamp" moves over the DNA increasing processivity.
(III) RNAPII accomplishes proofreading by forcing mispaired nucleotides against the
"wall" causing distortion such that mispairs can be cleaved by the "rudder."

A) I,II,III
B) I,II
C) II,III
D) II only
E) III only