Which of the Following Indicate Severely Impaired Oxygenation Requiring High

Multiple Choice

Which of the following indicate severely impaired oxygenation requiring high FiO₂s and positive end expiratory pressure?
1) PaO₂-PaO₂ greater than 350 mm Hg on 100% O₂
2) VC less than 10 ml/kg
3) PaO₂/FiO₂ less than 200
4) PaCO₂ greater than 45 mm Hg

A) 1 and 4 only
B) 1 and 3 only
C) 2 and 3 only
D) 1, 2, and 4 only